'El arte y las malas influenzas' by hesenrre
Photo by hesenrre

Egypt decided to slaughter all of their nation’s 300,000 pigs, President Obama asked Congress for $1.5 billion for flu preparedness, and China herded and quarantined 70 healthy Mexican nationals. But why? Is all the fear and preparation justifiable?

The initial numbers seemed to suggest so as reports highlighted the deaths in relation to the relatively few confirmed cases. But we now know that this new influenza A/H1N1 strain is currently no more deadly than the normal seasonal flu. As the hype is starting to wear down the focus in the media is switching from new infections to speculations regarding how the virus could change.

Influenza is a volatile virus. Its genes change rapidly through regular mutations. And when two different influenza strains infect the same host, they can swap and borrow bits of genetic material. This process, known as reassortment, compounds influenza’s unpredictability.

Sometimes reassortments led to new pandemics. It is possible that reassortment enables flu viruses to escape the immune system so well that they can make people sicker and spread faster to new hosts.

Reassortment also played a big role in the emergence of the current swine flu. Its genes come from several ancestors, which mainly infected pigs.

-New York Times, “10 Genes, Furiously Evolving”

When the reassortment occurs between two strains already endemic in the human population, the results tend to be less than extraordinary. But when unlike strains come together, just as bird, pig, and human strains formed the 1918 Spanish flu, the result can be extremely virulent.

So it’s a fair question to ask: what if this new strain of influenza A/H1N1 becomes more deadly? Even though there have only been 1490 confirmed cases and 30 deaths globally (WHO, 5 May 2009), governments continue preparations as if a deadly outbreak were imminent.

Should the outbreak take a turn for the worse, any government taking a more conservative stand would be hard pressed to justify any inaction. Erring on the side of caution, governments more readily hedge their bets.

Will this new influenza A/H1N1 virus become more deadly? It seems unlikely, but certainty tends to be a luxury of hindsight.